(Bio Mathematical Lab of Sikander Aqeel)
CHAPTER [3] PROTEINS
Proteins
(3/30/2016)
Amino Acid Composition of Proteins:
It is amazing that all the different types of proteins are initially synthesized as polymers of only 20 amino acids, known as the common amino acids, the common amino acids are defined as those amino acids for which a specific codon exists in the DNA genetic code, there are 20 amino acids for which DNA codon are known, the process of the reading of the DNA code, resulting in the polymerization of amino acids of a specific sequence into the proteins based on the DNA code, In this chapter we shall discus only the protein of this genetically controlled synthetic process,
For example
Glycine = C2H5NO2 = 76.25 m/g
Glycine = GGU, GGC, GGA, GGG, = mRNA Codons
(GUANINE)
= a2 + b2 = c2
= a2 = Glycine and b2 = Guanine = c2
= a2 = 76.25 m/g and b2 = 151.13 g/mol = c2
= a76.25 + b151.13 = c2
= 5814.0625 + 22840.2769 = c2
= a + b = 28654.3394 = c2
= a + b = 28654.3394 / 21.06 (H2O + H2) = 1360.17
= a + b = 1360.17 / 151.13 (G) = 9
= a + b = 9 Guanine from Glycine polymerization,
mRNA Glycine Non-Polar = 9 Guanine
tRNA Glycine Non-Polar = 0 Guanine
(CYTOSINE)
= a2 + b2 = c2
= a2 = Glycine and b2 = Cytosine = c2
= a2 = 76.25 m/g and b2 = 111.1 g/mol = c2
= a76.25 + b111.1 = c2
= 5814.0625 + 12343.21 = c2
= a + b = 18157.2725 = c2
= a + b = 18157.2725 / 163.43 (glycogenic 97.25 + O2 + N2 + H5) = 111.1
= a + b = 111.1 / 111.1 (C) = 1
= a + b = 1 Cytosine from Glycine polymerization,
mRNA Glycine Non-Polar = 1 Cytosine
tRNA Glycine Non-Polar = 0 Cytosine
(URACIL)
= a2 + b2 = c2
= a2 = Glycine and b2 = Uracil = c2
= a2 = 76.25 m/g and b2 = 112.0868 g/mol = c2
= a76.25 + b112.0868 = c2
= 5814.0625 + 12563.45073424 = c2
= a + b = 18377.51323424 = c2
= a + b = 18377.51323424 / 163.95 (Hemoglobin CO2 + H2O -> H+ + HCO3 [NH3 + CH2 + H5]) = 112.09
= a + b = 112.09 / 112.0868 (U) = 1
= a + b = 1 Uracil from Glycine polymerization,
mRNA Glycine Non-Polar = 1 Uracil
tRNA Glycine Non-Polar = 0 Uracil
(ADENINE)
= a2 + b2 = c2
= a2 = Glycine and b2 = Adenine = c2
= a2 = 76.25 m/g and b2 = 135.13 g/mol = c2
= a76.25 + b135.13 = c2
= 5814.0625 + 18260.1169 = c2
= a + b = 24074.1794 = c2
= a + b = 24074.1794 / 178.15 (3CH2OH + 82.9 enzymes) = 135.13
= a + b = 135.13 / 135.13 (A) = 1
= a + b = 1 Adenine from Glycine polymerization,
mRNA Glycine Non-Polar = 1 Adenine
tRNA Glycine Non-Polar = 0 Adenine
Total Codons = G9 + C1 + U1 + A1 + = 12
Glycine = GGU, GGC, GGA, GGG, = mRNA Codons
There are 20 amino acids for which mRNA codon are known, the process of the reading of the mRNA code, resulting in the polymerization of amino acids of a specific sequence into the proteins based on the mRNA code,
The genetically controlled synthetic process =
= (H2O + H2)
= (glycogenic 97.25 + O2 + N2 + H5)
= (Hemoglobin CO2 + H2O -> H+ + HCO3 [NH3 + CH2 + H5])
= (3CH2OH + 82.9 enzymes)
Main Functions of Glycine
Part of the stucture of hemoglobin, (Hemoglobin CO2 + H2O -> H+ + HCO3 [NH3 + CH2 + H5])
One of the two main inhibitory neurotransmitters, the other being GABA,
Part of cytochromes, which are enzymes involved in energy production, (3CH2OH + 82.9 enzymes)
Inhibits sugar cravings, (3CH2OH + 82.9 enzymes)
One of the 3 critical glycogenic 97.25 amino acids, along with serine and alanine, (glycogenic 97.25 + O2 + N2 + H5)
Involved in glucagon production, which assists in glycogen metabolism, (glycogenic 97.25 + O2 + N2 + H5) + (H2O + H2)