(Bio Mathematical Lab of Sikander Aqeel)
CHAPTER [3] PROTEINS
Proteins
(4/8/2016)
Amino Acid Composition of Proteins:
It is amazing that all the different types of proteins are initially synthesized as polymers of only 20 amino acids, known as the common amino acids, the common amino acids are defined as those amino acids for which a specific codon exists in the DNA genetic code, there are 20 amino acids for which DNA codon are known, the process of the reading of the DNA code, resulting in the polymerization of amino acids of a specific sequence into the proteins based on the DNA code, In this chapter we shall discus only the protein of this genetically controlled synthetic process,
For example
Phenylalanine = C9H11NO2 = 167.75 m/g
Phenylalanine = UUU, UUC, = mRNA Codons
(URACIL)
= a2 + b2 = c2 (Uracil)
= a2 = Phenylalanine and b2 = Uracil = c2
= a2 = 167.75 m/g and b2 = 112.0868 g/mol = c2
= a167.75 + b112.0868 = c2
= 28140.0625 + 12563.45073424 = c2
= a + b = 35591.51323424 = c2
= a + b = 40703.51323424 / 72.68 (H2O 18.5 + NH2 16.5 + H1 = 72.5) = 560
= a + b = 560 / 112 (U) = 5
= a + b = 5 Uracil for mRNA Phenylalanine,
mRNA Phenylalanine Non-polar = 5 Uracil
tRNA Phenylalanine Non-polar = 0 Uracil
(CYTOSINE)
= a2 + b2 = c2
= a2 = Phenylalanine and b2 = Cytosine = c2
= a2 = 167.75 m/g and b2 = 111.1 g/mol = c2
= a167.75 + b111.1 = c2
= 28140.0625 + 12343.21 = c2
= a + b = 40483.2725 = c2
= a + b = 40483.2725 / 364.38 (2(C6H12O6) = 366 – 2 H = 364) = 111.1
= a + b = 111.1 / 111.1 (C) = 1
= a + b = 1 Cytosine for mRNA Phenylalanine,
mRNA Phenylalanine Non-polar = 1 Cytosine
tRNA Phenylalanine Non-polar = 0 Cytosine
Total Codons = U5 + C1 + = 6
Phenylalanine = UUU, UUC, = mRNA Codons
There are 20 amino acids for which mRNA codon are known, the process of the reading of the mRNA code, resulting in the polymerization of amino acids of a specific sequence into the proteins based on the mRNA code,
The genetically controlled synthetic process =
= (H2O 18.5 + NH2 16.5 + H1 = 72.5)
= (2(C6H12O6) = 366 – 2 H = 364)
Main Functions of Phenylalanine
Suppresses appetite, (2(C6H12O6) = 366 – 2 H = 364)
Major part of collagen formation, (H2O 18.5 + NH2 16.5 + H1 = 72.5)
While the L-form of all of the other amino acids is the one that is beneficial to people, the
D and DL forms of Phenylalanine have been useful in treating pain.
DL-Phenylalanine is useful in reducing arthritic pain. (2(C6H12O6) = 366 – 2 H = 364)
Powerful anti-depressant, (2(C6H12O6) = 366 – 2 H = 364)
Used in the treatment of Parkinson's Disease.