(Bio Mathematical Lab of Sikander Aqeel)
CHAPTER [3] PROTEINS
Proteins
(4/10/2016)
Amino Acid Composition of Proteins:
It is amazing that all the different types of proteins are initially synthesized as polymers of only 20 amino acids, known as the common amino acids, the common amino acids are defined as those amino acids for which a specific codon exists in the DNA genetic code, there are 20 amino acids for which DNA codon are known, the process of the reading of the DNA code, resulting in the polymerization of amino acids of a specific sequence into the proteins based on the DNA code, In this chapter we shall discus only the protein of this genetically controlled synthetic process,
For example
Serine = C3H7NO3 = 106.75 m/g
Serine = UCU, UCC, UCA, UCG, AGU, AGC, = mRNA Codons
(GUANINE)
= a2 + b2 = c2
= a2 = Serine and b2 = Guanine = c2
= a2 = 106.75 m/g and b2 = 151.13 g/mol = c2
= a106.75 + b151.13 = c2
= 11395.5625 + 22840.2769 = c2
= a + b = 34235.8394 = c2
= a + b = 34235.8394 / 75.51 (1CH2OH + NH3 + H2O + H6) = 453.39
= a + b = 453.39 / 151.13 (G) = 3
= a + b = 3 Guanine for mRNA Serine,
mRNA Serine Polar = 3 Guanine
tRNA Serine Polar = 0 Guanine
(CYTOSINE)
= a2 + b2 = c2
= a2 = Serine and b2 = Cytosine = c2
= a2 = 106.75 m/g and b2 = 111.1 g/mol = c2
= a106.75 + b111.1 = c2
= 11395.5625 + 12343.21 = c2
= a + b = 23738.7725 = c2
= a + b = 23738.7725 / 35.61 (P + H4) = 666.6
= a + b = 666.6 / 111.1 (C) = 6
= a + b = 6 Cytosine for mRNA Serine,
mRNA Serine Polar = 6 Cytosine
tRNA Serine Polar = 0 Cytosine
(ADENINE)
= a2 + b2 = c2
= a2 = Serine and b2 = Adenine = c2
= a2 = 106.75 m/g and b2 = 135.13 g/mol = c2
= a106.75 + b135.13 = c2
= 11395.5625 + 18260.1169 = c2
= a + b = 29655.6794 = c2
= a + b = 29655.6794 / 73.15 (2CH2OH + H8) = 405.39
= a + b = 405.39 / 135.13 (A) = 3
= a + b = 3 Adenine for mRNA Serine,
mRNA Serine Polar = 3 Adenine
tRNA Serine Polar = 0 Adenine
(URACIL)
= a2 + b2 = c2
= a2 = Serine and b2 = Uracil = c2
= a2 = 106.75 m/g and b2 = 112.0868 g/mol = c2
= a106.75 + b112.0868 = c2
= 11395.5625 + 12563.45073424 = c2
= a + b = 23959.01323424 = c2
= a + b = 23959.01323424 / 35.65 (H2O + NH3) = 672
= a + b = 672 / 112 (U) = 6
= a + b = 5 Uracil for mRNA Serine,
mRNA Serine Polar = 5 Uracil
tRNA Serine Polar = 0 Uracil
Total Codons = G3 + C6 + U6 + A3 + = 18
Serine = UCU, UCC, UCA, UCG, AGU, AGC, = mRNA Codons
There are 20 amino acids for which mRNA codon are known, the process of the reading of the mRNA code, resulting in the polymerization of amino acids of a specific sequence into the proteins based on the mRNA code,
The genetically controlled synthetic process =
= (1CH2OH + NH3 + H2O + H6)
= (P + H4)
= (2CH2OH + H8)
= (H2O + NH3)
Main Functions of Serine
One of the 3 most important glycogenic amino acids,
the others being alanine and glycine,
Critical in maintaining blood sugar levels, (2CH2OH + H8)
Boosts immune system by assisting in production of antibodies and immunoglobulins.
Myelin sheath (the fatty acid complex that surrounds the axons of nerves is derived from serine.
One variation of Serine namely Phosphotidyl Serine, (P + H4)
a minor amino acid serves several important functions within the central nervous system, (1CH2OH + NH3 + H2O + H6)
including development of the myelin sheath.
Multiple Sclerosis is one of the so-called "De-myelinating Diseases."
Required for growth and maintenance of muscle, (2CH2OH + H8)
The amino acid Glycine is a precursor to Serine and the two are interconvertible.
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