(Bio Mathematical Lab of Sikander Aqeel)
CHAPTER [3] PROTEINS
Proteins
(4/21/2016)
Amino Acid Composition of Proteins:
It is amazing that all the different types of proteins are initially synthesized as polymers of only 20 amino acids, known as the common amino acids, the common amino acids are defined as those amino acids for which a specific codon exists in the DNA genetic code, there are 20 amino acids for which DNA codon are known, the process of the reading of the DNA code, resulting in the polymerization of amino acids of a specific sequence into the proteins based on the DNA code, In this chapter we shall discus only the protein of this genetically controlled synthetic process,
In addition to the common amino acids, derived amino acids are found in proteins, derived amino acids are found from one of the common amino acids, usually by an enzyme-facilitated reaction, after the common amino acids has been incorporated into the proteins structure, an example of a derived amino acids Cystine, other derived amino acids are desmosine and isodesmosine found in protein elastin,
The hydroxyproline and hydroxylysine found in Collagen and Y-carboxyglutamate found in prothrombin,
Regular Structure of the Common Amino Acids,
The common amino acids have the regular structure, they contain on common a central (Alpha) carbon atom, to which a carboxyl acid group an amino group, and a hydrogen atom are covalently bonded, the (Alpha) a-carbon atom binds a side chain group designated R, that is different for each of the 20 amino acids,
GLYCINE ENZYMES, HEAM, GLOBIN, AND HEMOGLOBIN
The enzymes are kind of Time-acids, the world of enzymes belongs with 48 hours of one day, if your age is 48 year today, that your enzymes has worked 96 years, and this process increases to age system, and from this reason the enzymes speed occurs faster for catalyst,
Glycine = NH2-CH2-COOH = 76.25 mole grams
Glycine enzymes = 48 hours time of dabble speed
= a2 + b2 = c2
= a Glycine + b time = c2
= a76.25 + b48 hours = c2
= a5814.0625 + b2304 = c2
= a + b = 8118.0625 = c2
= a + b = 8118.0625 / 90.100 = 90.100
Enzymes number = 90.100 * 90.100 = 8118.0625
Enzymes number = Time * Amino Acid = 8118.0625
Glycine enzymes number = 8118.0625
HEMOGLOBIN
Blood plasma = 7.4 pH
68.125 gene = 0.545 (68.125 * 0.008 Photons = 0.545)
Total = 7.945
= a2 + b2 = c2
= a Glycine + b time = c2
= a76.25 + b48 hours = c2
= a5814.0625 + b2304 = c2
= a + b = 8118.0625 = c2
= a + b = 8118.0625 * 7.945 = 64498.00
= a + b = 64498.00 + 2 = 64500.00
= a + b = 64500.00 = molecular weight of hemoglobin
DIVISION OF HEAM AND GLOBIN
Heam = two Iron = Fe2 = 56 + 56 = 112
Globin = proteins = 576 polypeptide chain
Hemoglobin = 64500.00 / 112 Fe2 = 575.89
= 576 / 7.4 pH = 77.83
= 77.83 - 1.58 H1 = 76.25
= 76.25 = Glycine amino acids
Main Functions of Glycine:
Part of the structure of hemoglobin,
GENETIC CODE FROM GLYSINE
16 permutation of four-Letter code taken by pairs
Human bones = 206
Human chromosomes = 46.25
Glysine = 76.25
Guanine = 151.13 g/mol = (G)
Human bones = 206 * 46.25 = 9527.5
= 9527.5 = total genetic codes of 206 bones,
= a2 + b2 = c2
= a2 genetic codes + b2 Glysine = c2
= a2 9527.5 + b2 76.25 = c2
= 90773256.25 + 5814.0625 = c2
= 90773256.25 + 5814.0625 = c2
= a + b = 90779070.3125 = c2
= a + b = 90779070.3125 / 9528 = 9528
= 9528 / 151.13 (G) = 63.04
= 63 / 5.25 gene = 12
= 12 = GGU, GGC, GGA, GGG,
= genetic mutation = 5.25 gene by Glysine
= genetic mutation = 5.25 gene into the artery cells,
So 10.5 genes happening disorder per day by law of enzymes speed,
SEARCH OF GENETIC MUTATION
Enzymes speed = 120 minute (by 48 hours a day)
Guanine = 151.13
= a2 + b2 = c2
= a2 enzymes + b2 G = c2
= a2 120 + b2 151.13 = c2
= 14400 + 22840.2769 = c2
= 14400 + 22840.2769 = c2
= a + b = 37240.2769 = c2
= a + b = 37240.2769 / 193 = 193
= 193 / 18.5 (H2O) = 10.43
= 10.5 = gene,
So 10.5 genes happening disorder per day by law of enzymes speed,
OCCIPITAL ARTERY GLYSINE AND GENES
Here we shall find total water total genes total Glysine units of Occipital artery,
Occipital artery length = nearly 13 Inch (by all branches)
Occipital artery thickness = nearly 2 points of Inch in healthy age
One inch = 8 points
One gene = 0.008 size of photon
Hemoglobin = 64500.00 / 18.5 = 3486.48
= 3487 / 76.25 = 45.73
= 45.73 - 0.48 = 45.25
= 45.25 = COOH
Algebra
= a1 + b2 = c2
= a1 Hemoglobin + b2 water = c2
= a1 64500.00 + b2 18.5 = c2
= a1 64500 + b2 342.25 = c2
= a + b = 64842.25 = c2
= a + b = 64842.25 / 254.6 = 254.6
= a + b = 254.6 / 15.96 = 15.96
= a + b = 15.96 = Oxygen
= a + b = 15.96 = Oxygen of Hemoglobin
Water in hemoglobin = 3487 units
Glysine in water = 45.25 units
Water in hemoglobin = 3487 * 13 = 45331
= 45331 * 2 = 90662
= 90662 units water in Occipital artery
Algebra
= a1 + b2 = c2
= a1 water + b2 length artery = c2
= a1 3487 + b2 13 = c2
= a1 3487 + b2 169 = c2
= a + b = 3656 = c2
= a + b = 3656 / 60.46 = 60.46
= a + b = 60.46 / 7.78 = 7.78
= a + b = 7.78 - 0.38 = 7.4
= a + b = 7.4 = pH of Hemoglobin
Water of Occipital artery = 90662 / 0.008 = 11332750
= 11332750 genes in Occipital artery
Because if photon is in water, that photon is a gene, if photon is in space, then photon is a particle,
Because = 11332750 genes / 68.25 = 166047.61
= 166048 / 2.57 H2 of DNA = 64610.11
= 64610 – 110 gene = 64500 molecular weight of hemoglobin
= a2 / b2 = c2
= a2 total genes / b2 enzymes time = c2
= a2 11332750 / b2 120 seconds = c2
= 128431222562500 / 14400 = c2
= 128431222562500 / 14400 = c2
= a / b = 8918834900 = c2
= a / b = 8918834900 / 94439.5 = 94439.5
= 94439.5 - 90662 (H2O) = 3777.5
= 3777.5 / 49.5 unit of Gly = 76.3
= 76.25 = Glysine
A healthy Occipital artery need = 90662 units hemoglobin water per day
A healthy Occipital artery need = 11332750 genes per day
A healthy Occipital artery need = 49.5 or 45.25 units of Glysine per day
Because = 90662 / 24 h / 60 m / 60 sec = 1.04 day
Because = 11332750 / 90662 = 125 / 2 point thickness = 62.5 – 2.5 H2 = 60 seconds of a minute,
Because = 11332750 / 90662 = 125 * 0.008 photon or gene = 1 day,
The Occipital artery controls to vision senses, through the 11332750 genes, 90662 unit water and 49.5 or 45.25 units of Glysine per day, the salts of hemoglobin creates heat in artery, then artery deletes oxygen into the brain cells, and wet brain cells increases function of nervous system for messages of need of body,
It was simple which you will have understood, now important is why a old person cannot see easily, while 90662 unit water is present into the artery, actually 90662 unit water reaction is 1.25 day or hydrogen atom in little age, and old age reaction belongs with (HPO4) mono-hydrogen phosphate ions, and this mono-hydrogen phosphate ions becomes gather into the artery cells to shut the artery,
For example
Little age = 1.25 year old cells * 90662 unit = 113327.5
= 113327.5 / 24 h / 60 m / 60 sec = 1.31 one hydrogen atom
Old age = 92 year old cells * 90662 unit = 8340904
= 8340904 / 24 h / 60 m / 60 sec = 96.5 one mono-hydrogen phosphate ions,
Always remember my words, that old cells and new fresh cells are two important branches of biology, or your study should be contain on two types cells, young and old cells,