(Two Polynucleotide in mathematical machine of Sikander Aqeel)
two POLYNUCLEOTIDE:
WILSON DISEASE (7/21/2016)
Lower-than-normal ALP levels
• 1 = Hypophosphatasia
• 2 = Malnutrition
• 3 = Wilson disease
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• Wilson disease has a range of clinical manifestations, from an asymptomatic state to fulminate hepatic failure, chronic liver disease with or without cirrhosis, neurologic, and psychiatric manifestations
• Consider hepatic Wilson disease in the differential diagnosis of any unexplained chronic liver disease, especially in individuals younger than 40 years. The condition may also manifest as acute hepatitis. Hepatic dysfunction is the presenting feature in more than half of patients. The 3 major patterns of hepatic involvement are as follows: (1) chronic active hepatitis, (2) cirrhosis, and (3) fulminant hepatic failure. The most common initial presentation is cirrhosis.
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So the Malnutrition goes in tuberculosis, gastroenteritis, pneumonia, malaria, and measles, and thsese all infections goes in definicey of proteins and vitamins for rise-up Wilson disease, like
• Patients in the parkinsonian group (45%) - Distinguished by paucity of expression and movement
• Patients in the pseudosclerotic group (24%) - Had tremor resembling multiple sclerosis
• Patients in the dystonic group (15%) - Characterized by hypertonicity associated with abnormal limb movements.
• Patients in the choreic group (11%) - Predominantly characterized by choreoathetoid abnormal movements associated with dystonia
Psychiatric features include emotional lability, impulsiveness, disinhibition, and self-injurious behavior. The reported percentage of patients with psychiatric symptoms as the presenting clinical feature is 10-20%. The range of psychiatric abnormalities associated with Wilson disease has been divided into 4 basic categories, as follows:
• Behavioral
• Affective
• Schizophrenic-like
• Cognitive
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PATIENTS IN THE DYSTONIC GROUP (15%)
= Characterized by hypertonicity associated with abnormal limb movements,
The multiple sclerosis involves an immune-mediated process in which body shows an abnormal response,
When any part of the myelin sheath or nerve fiber is damaged or destroyed, nerve impulses traveling to end from the brain and spinal cord are distorted or interrupted, producing a wide variety of symptoms,
MS is a long-lasting disease that can affect your brain, spinal cord, and the optic nerves in your eyes. It can cause problems with vision, balance, muscle control, and other basic body functions.
The effects are often different for everyone who has the disease. Some people have mild symptoms and don’t need treatment. Others will have trouble getting around and doing daily tasks
MS = defect of brain
MS = defect of optic nerves for vision from occipital lobe
MS = defect of balance from cerebellum lobe
MS = defect of muscle control or temperature from brain stem
MS first main defected place = brain stem
MS happens when your immune system attacks a fatty material called myelin, which wraps around your nerve fibers to protect them. Without this outer shell, your nerves become damaged. Scar tissue may form.
The damage means your brain can’t send signals through your body correctly. Your nerves also don’t work as they should to help you move and feel. As a result, you may have symptoms like:
• Trouble walking
• Feeling tired
• Muscle weakness or spasms
• Blurred or double vision
• Numbness and tingling
• **ual problems
• Poor bladder or bowel control
• Pain
• Depression
MS = defect of brain
MS = defect of optic nerves for vision from occipital lobe
MS = defect of balance from cerebellum lobe
MS = defect of muscle control or temperature from brain stem
MS first main defected place = brain stem
MS second main defected reason = fatty material
MS third main defected place = nerves system
MS fourth main defected act = signals nerves in whole body
MS total defect = brain + occipital lobe + cerebellum lobe + brain stem
MS total defect = brain stem + fatty material + nerves system + signals
MS total defect = brain + brain stem
MS total defect = occipital lobe + nerves system
MS total defect = cerebellum lobe + fatty material
MS total defect = brain stem + signals
TOTAL RESULT OF MULTIPLE SCLEROSIS
The multiple sclerosis diseases begin between complete brain and brain stem. Which rise up to nerves disease to produce fatty acid, and fatty acids shuts the door of signals and without signals the body becomes abnormal,
Multiple sclerosis diseases = abnormal or slow body
Abnormal or slow body = sick Parasympathetic nerve system = over age
Parasympathetic nerve system = to increase heartbeat
Parasympathetic nerve system = to increase bloodstream
Parasympathetic nerve system = to increase glucose in blood,
TREATMENT OF MULTIPLE SCLEROSIS
MS total defect = brain + brain stem = Parasympathetic nerve system
MS total defect = occipital lobe + nerves system = to increase heartbeat
MS total defect = cerebellum lobe + fatty material = to increase bloodstream
MS total defect = brain stem + signals = to increase glucose in blood
1 = when we increase value of Parasympathetic nerve system, then brain arteries will be active for to be normal,
2 = when we will increase value of heartbeat, then optic nerve will be active for normal vision,
3 = when we will increase value of bloodstream, then fatty acid will be gone in fat for balance,
4 = when we increase value of glucose in blood, then nerve signals will be active for come in normal condition, by muscle control or temperature
Parasympathetic nerve system = Cranial nerves = 12 joints of motor nerve
GLUCOSE IN BLOOD (7/21/2016)
FOR EXAMPLE BEGINNING OF ENERGY,
Adenine + ribose sugar
A = energy
= a2 + b2 = c2
= a2 (Adenine) + b2 ribose sugar = c2
= a2 (C5H5N5) + b2 (C5H10O4) = c2
= a2 (135.13 g/mol) + b2 (136.5 g/mol) = c2
= a2 (18260.1169) + b2 (18632.25) = c2
= a + b = 36892.3669 = c2
= a + b = 36892.3669 / 45.25 (COOH) = 815.300
= a + b = 815
B = Phosphate
= a2 / b2 = c2
= a2 (815) / b2 (PO4) = c2
= a2 (815) / b2 (95) = c2
= a2 (664225) / b2 (9025) = c2
= a / b = 73.59 = c2
= a / b = 74 / 8.60 = 8.60
= a / b = 8.60 / 2.5 (H2= A//T DNA) = 3.44
= a / b = 3.44 + 0.31 = 3.75
= a / b = 3.75 = (H3= C///G DNA)
= a / b = (H2= A//T DNA) + (H3= C///G DNA) = two Polynucleotide chains,
= a / b = (H2= A//T DNA) + (H3= C///G DNA) = end of energy,
C = GLUCOSE IN BLOOD = 1355 / 7.4 pH of plasma = 183 glucose
= a2 / b2 = c2
= a2 (183 glucose) / b2 (two Polynucleotide) = c2
= a2 (1355) / b2 (2.5 + 3.75) = c2
= a2 (1355) / b2 (6.25) = c2
= a2 (1836025) / b2 (39.0625) = c2
= a / b = 47002.24 = c2
= a / b = 47002.24 / 216.75 = 216.85
While 216.85 / 31.75 = 6.8(CH2OH) fructose
CONDITION OF DNA
= a / b = 216.85 / 2.5 (H2= A//T DNA) = 86.74
= a / b = 86.74 / 3.75 (H3= C///G DNA) = 23.13
= a / b = 23.13 * 50 ratio = 1156.5
= a / b = 1156.5 / 34.01A = 34A
= a / b = 34A = distance of one helix
= Chemosynthetic bacteria = 34A / 10 mononucleotide = 3.4
= = 3.4A distance between two base pair,
Trouble walking = need of 7.4 pH and 7.4 unit glucose in blood
Feeling tired = need of 7.4 pH and 7.4 unit glucose in blood
Muscle weakness or spasms = need of 7.4 pH and 7.4 unit glucose in blood
Blurred or double vision = need of 7.4 pH and 7.4 unit glucose in blood
• Numbness and tingling
**ual problems = need of 7.4 pH and 7.4 unit glucose in blood
Poor bladder or bowel control = need of 7.4 pH and 7.4 unit glucose in blood
• Pain = need of 7.4 pH and 7.4 unit glucose in blood
• Depression = need of 7.4 pH and 7.4 unit glucose in blood,
Always remember my biological words, that where occurs fiver of cold, there these all diseases are common, and where occurs fiver of heat, that there will not present these all diseases,
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For easiness and remembrances
0 = normal lower range = 44 = ALP – blood test
• 1 = Hypophosphatasia lower range = 43, 40, 39, ALP – blood test
• 2 = Protein deficiency lower rang = 38, 37, ALP – blood test
• 3 = Malnutrition lower range = 36, 35, ALP – blood test
• 4 = Wilson disease lower range =
And we can change rate at the end for Wilson disease,
OTHER CONDITIONS FOR WHICH THE TEST MAY BE MORE DONE:
• Alcoholic liver disease (hepatitis/cirrhosis)
• Alcoholism
• Biliary stricture
• Gallstones
• Giant cell (temporal, cranial) arteritis
• Multiple endocrine neoplasia (MEN) II
• Pancreatitis
• Renal cell carcinoma