(Two Polynucleotide in mathematical machine of Sikander Aqeel)
WILSON DISEASE
Lower-than-normal ALP levels
• 1 = Hypophosphatasia
• 2 = Malnutrition
• 3 = Wilson disease
•
• Wilson disease has a range of clinical manifestations, from an asymptomatic state to fulminate hepatic failure, chronic liver disease with or without cirrhosis, neurologic, and psychiatric manifestations
• Consider hepatic Wilson disease in the differential diagnosis of any unexplained chronic liver disease, especially in individuals younger than 40 years. The condition may also manifest as acute hepatitis. Hepatic dysfunction is the presenting feature in more than half of patients. The 3 major patterns of hepatic involvement are as follows:
• (1) chronic active hepatitis,
• (2) cirrhosis, and
• (3) fulminant hepatic failure. The most common initial presentation is cirrhosis.
2 = CIRRHOSIS (8/12/2016)
• Definitions of cirrhosis
• noun
• A chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue. It is typically a result of alcoholism or hepatitis.
• Chronic viral hepatitis is the main cause of chronic liver disease, cirrhosis and hepatocellular carcinoma throughout the world.
Symptoms caused by ac**ulations in liver or kidneys include:
• hypoglycemia
• kidney dysfunction
• jaundice (caused by liver failure)
• cirrhosis of the liver
Alcoholism = affect of alcohol on human system = -OH single = 17.25
Urease enzyme + Arginase enzyme = liver function
Urease enzyme = liver = Urea = 7.0 optimum pH
Arginase enzyme = liver = Arginine substreat = 9.7 optimum pH
Arginine = C6H14N4O2 = 177.5 m/g
= a2 + b2 = c2
= a2 Arginine + b2 Urease plus Arginase enzyme = c2
= a2 177.5 + b2 16.7 = c2
= a2 31506.25 + b2 278.89 = c2
= a + b = 31785.14 = c2
= a + b = 31785.14 / 178.28 = 178.28
= a + b = 178.28 / 2.5 (H2= A//T DNA) = 71.312
= a + b = 71.312 / 1.114 % copper in liver = 64.01
= a + b = 64.01 = Cu = Copper of liver
MENKEN’S SYNDROME
It certainly hereditary disease, where copper does not active in whole body, and liver also does not gather normal quantity of copper, where diseases rise-up like brain disorders, reduction of hair, cold body, plasma, and liver, for Anemia, less proteins, less quantity of red cells in blood,
Such as liver becomes fail from jaundice, from reason of reduction of copper in liver,
Arginine = 177.5 * 7.0 Enzyme optimum pH = 1242.5
= 1242.5 * 9.7 Enzyme optimum pH = 12052.25
= 12052.25 / 64 Cu = 188.31640625
= 188.31 - 5.31 = 183 sugar of liver
= 183 = C6H12O6 sugar from reason of Insulin, if insulin is not present, then sugar will not,
So if we do less optimum pH of liver enzymes, then sugar gathering system will be failed in liver,
ABOUT CHOLESTASIS (8/16/2016)
Cholestasis means any condition in which bile flow is reduced or stopped. "Chole" refers to bile and "stasis" means "not moving." Bile flow may be blocked inside the liver, outside the liver, or in both places. Symptoms may include:
• Jaundice
• Dark urine
• Pale stool
• Easy bleeding
• Itching
• Ascites
• Chills
• Pain from the biliary tract or pancreas
• Enlarged gallbladder
Some causes of cholestasis include the following:
• Hepatitis
• Alcoholic liver disease
• Primary biliary cirrhosis
• Drug effects
• Hormonal changes during pregnancy
• A stone in the bile duct
• Bile duct narrowing
• Bile duct cancer
• Pancreatic cancer
• Inflammation of the pancreas
CLAY-COLORED PALE STOOLS
The non-Jaundice health depend on high Arginine, and less Arginine in blood causes of jaundice disease,
Arginine = C6H14N4O2 = 177.5 m/g
Arginine = 177.5 / 100 % = 1.775
= 2.935 * 30 % = 88.05
= 88.05 m/g = 30 percent Arginine
Urease enzyme = liver = Urea = 7.0 optimum pH
Arginase enzyme = liver = Arginine substreat = 9.7 optimum pH
Urease + Arginase enzyme = 16.7 optimum pH
30 % Arginine = 88.05 m/g
= a2 + b2 = c2
= a2 30 % Arginine + b2 Urease plus Arginase enzyme = c2
= a2 88.05 + b2 16.7 = c2
= a2 7752.8025 + b2 278.89 = c2
= a + b = 8031.6925 = c2
= a + b = 8031.6925 / 89.61 = 89.62
= a + b = 89.62 / 2.5 (H2= A//T DNA) = 35.848
= a + b = 35.848 / 3.75 (H3= C///G DNA) = 9.55
= a + b = 10 * 50 ratio = 500
= a + b = 500 / 22.36A = 22.36A
= a + b = 22A = weak height of helix
= Arginine = 22A / 10 mononucleotide = 2.2
= = 2.2A weak distance between two base pair,
• So the 30 percent Arginine doing small or short to helix of DNA, and doing clay-colored to Pale stool to rise up more yellow color of jaundice,
For example
Urease enzyme = liver = Urea = 7.0 optimum pH
Arginase enzyme = liver = Arginine substreat = 9.7 optimum pH
Urease + Arginase enzyme = 16.7 optimum pH
30 % Arginine = 88.05 m/g
= a2 + b2 = c2
= a2 30 % Arginine + b2 Urease plus Arginase enzyme = c2
= a2 88.05 + b2 16.7 = c2
= a2 7752.8025 + b2 278.89 = c2
= a + b = 8031.6925 = c2
= a + b = 8031.6925 * 6.2 optimum pH of small intestine sucrase enzyme = 49796.4935
= a + b = 49796.49 * 1.295 H = 64486.45
= a + b = 64486.45 + 13.55 N = 64500
= a + b = 64500 molecular weight of hemoglobin,
So here 6.2 optimum pH of small intestine sucrase enzyme and hydrogen nitrogen is becoming clay-colored potty from reason of sick helix of DNA,
• When the liver cells secrete bile, it is collected by a system of ducts that flow from the liver through the right and left hepatic ducts.
• These ducts ultimately drain into the common hepatic duct.
• The common hepatic duct then joins with the cystic duct from the gallbladder to form the common bile duct, which runs from the liver to the duodenum (the first section of the small intestine).
•
• Normal stools can vary in shades of brown, mostly due to diet. Pale or clay-colored stools are not normal. If your stools are pale or clay-colored, you may have a problem with the drainage of your biliary system, which is comprised of your gallbladder, liver, and pancreas.
• Bile salts are released into your stools by your liver, giving the stools a brown color. If your liver is not producing enough bile, or if the flow of the bile is blocked and not draining from your liver, your stools will be pale or clay-colored.
• Having pale or clay-colored stools once in a while may not be a cause for concern. If it occurs frequently, you may have a serious illness. You should see your doctor whenever you have pale or clay-colored stools in order
ALP - BLOOD TEST
Normal Results (ALP) tissues protein
The normal range is 44 to 147 IU/L (international units per liter)
The normal range = 147 IU/L for maximum weight and young age
The normal range = 44 IU/L for minimum weight and over age
NON-JAUNDICE HEALTHY LIVER
ARGININE IN ALP BLOOD TEST (LOWER)
(ALP) tissues protein = 44 * 2.00 (H2) = 88.05
= 88 + 0.05 = 88.05
= 88.05 m/g = 30 % Arginine,
DANGER-JAUNDICE
ARGININE IN ALP BLOOD TEST (HIGHER)
(ALP) tissues protein = 147 * 0.598 half hydrogen = 87.906
= 87.906 + 0.144 = 88.05
= 88.05 m/g = 30 % Arginine,