(Two Polynucleotide in mathematical machine of Sikander Aqeel)
WILSON DISEASE
Lower-than-normal ALP levels
• 1 = Hypophosphatasia
• 2 = Malnutrition
• 3 = Wilson disease
•
• Wilson disease has a range of clinical manifestations, from an asymptomatic state to fulminate hepatic failure, chronic liver disease with or without cirrhosis, neurologic, and psychiatric manifestations
• Consider hepatic Wilson disease in the differential diagnosis of any unexplained chronic liver disease, especially in individuals younger than 40 years. The condition may also manifest as acute hepatitis. Hepatic dysfunction is the presenting feature in more than half of patients. The 3 major patterns of hepatic involvement are as follows:
• (1) chronic active hepatitis,
• (2) cirrhosis, and
• (3) fulminant hepatic failure. The most common initial presentation is cirrhosis.
2 = CIRRHOSIS (8/12/2016)
• Definitions of cirrhosis
• noun
• A chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue. It is typically a result of alcoholism or hepatitis.
• Chronic viral hepatitis is the main cause of chronic liver disease, cirrhosis and hepatocellular carcinoma throughout the world.
ABOUT CHOLESTASIS (8/23/2016)
Cholestasis means any condition in which bile flow is reduced or stopped. "Chole" refers to bile and "stasis" means "not moving." Bile flow may be blocked inside the liver, outside the liver, or in both places. Symptoms may include:
• Jaundice
• Dark urine
• Pale stool
• Easy bleeding
• Itching
• Ascites
• Chills
• Pain from the biliary tract or pancreas
• Enlarged gallbladder
Some causes of cholestasis include the following:
• Hepatitis
• Alcoholic liver disease
• Primary biliary cirrhosis
• Drug effects
• Hormonal changes during pregnancy
• A stone in the bile duct
• Bile duct narrowing
• Bile duct cancer
• Pancreatic cancer
• Inflammation of the pancreas
ALCOHOLIC LIVER DISEASE
TERTIARY NATURAL ALCOHOL
The Alcoholic liver disease with Urease and Arginase enzymes of liver, while Tertiary natural Alcohol being use for disease,
Tertiary Alcohol = C4-OH = 65.25 m/g
Tertiary Alcohol = 65.25 / 100 % = 0.6525
= 0.6525 * 436.78 % = 285
= 285 m/g = 436.78 percent Alcohol
Urease enzyme = Liver = 8.0 optimum pH = (substrate = Urea)
Arginase enzyme = Liver = 9.7 optimum pH = (substrate = Arginine amino acids)
Urease + Arginase enzyme = 17.7 optimum pH
436.78 % Alcohol = 285 m/g
= a2 + b2 = c2
= a2 (436.78 % Alcohol) + b2 (Urease + Arginase enzyme) = c2
= a2 285 + b2 17.7 = c2
= a2 81225 + b2 313.29 = c2
= a + b = 81538.29 = c2
= a + b = 81538.29 / 285.54 = 285.55
= a + b = 285.55 / 2.5 (H2= A//T DNA) = 114.22
= a + b = 114.22 / 3.75 (H3= C///G DNA) = 30.45
= a + b = 30.45 * 50 ratio = 1522.5
= a + b = 1522.5 / 39.03A = 39A
= a + b = 39A = healthy height of helix
= Alcohol = 39A / 10 mononucleotide = 3.9
= = 3.9A healthy distance between two base pair,
Large helix of DNA from over alcohol in blood,
For example
Urease enzyme = Liver = 8.0 optimum pH = (substrate = Urea)
Arginase enzyme = Liver = 9.7 optimum pH = (substrate = Arginine amino acids)
Urease + Arginase enzyme = 17.7 optimum pH
436.78 % Alcohol = 285 m/g
= a2 + b2 = c2
= a2 (436.78 % Alcohol) + b2(Urease + Arginase enzyme) = c2
= a2 285 + b2 17.7 = c2
= a2 81225 + b2 313.29 = c2
= a + b = 81538.29 = c2
= a + b = 81538.29 – 64500 m/g hemoglobin = 17038.29
= a + b = 17038.29 = toxic substances building up in the blood
Diseases Liver enlargement
= a + b = 17038.29 / 9.7 pH of arginsea enzymes of liver = 1756.52
= a + b = 1756.52 / 7.0 pH of Urease enzymes of Urea = 250.93
= a + b = 251 / 8.0 pH of Lipase enzymes of pancreas = 31.375
= a + b = 31.375 + 0.375 = 31.75
= a + b = 31.75 = CH2OH = fructose,
So 39A height of helix and 3.9A distance of base pair are increasing of liver, Urea, and pancreas diseases, while Liver enlargement disease is continuous,
Liver enlargement is usually an indicator of liver disease, although there are usually no symptoms associated with a slightly enlarged liver (hepatomegaly). Symptoms of a grossly enlarged liver include abdominal discomfort or "feeling full."
After enlargement of liver the Liver encephalopathy diseases rise-up, such as changes of logical thinking, personality, and behavior,
Liver encephalopathy is the deterioration of brain function and damage to the nervous system due to toxic substances building up in the blood, which are normally removed by the liver. Liver encephalopathy is also called portal-systemic encephalopathy, hepatic encephalopathy, or hepatic coma. Symptoms may include:
• Impaired consciousness
• Changes in logical thinking, personality, and behavior
• Mood changes
• Impaired judgment
• Drowsiness
• Confusion
• Sluggish speech and movement
• Disorientation
• Loss of consciousness
• Coma
• Seizures (rare)
• Muscle stiffness or tremors
• Uncontrollable movement
Tertiary Alcohol = 331.08 % for healthy functions
Increased Alcohol = 105.7 % for Liver encephalopathy
Total Alcohol = 436.78 = 39A and 3.9A = damage to the nervous system due to toxic substances building up in the blood, and it is naturally by increment of natural alcohol,
For example! You took 105.7 % extra alcohol through the medicines, then Liver encephalopathy disease rise-up with Changes in logical thinking, personality, and behavior, from reason of large helix of DNA 39A and 3.9A,
ALP - BLOOD TEST
Normal Results (ALP) tissues protein
The normal range is 44 to 147 IU/L (international units per liter)
The normal range = 147 IU/L for maximum weight and young age
The normal range = 44 IU/L for minimum weight and over age
HEALTHY LIVER
OVER ALCOHOL IN ALP BLOOD TEST (LOWER)
(ALP) tissues protein = 44 * 6.47 (pH of small intestine) = 284.68
= 285 m/g = 436.78 % over Alcohol,
LIVERE
OVER ALCOHOL IN ALP BLOOD TEST (HIGHER)
(ALP) tissues protein = 147 * 1.938 (pepsine optimum pH) = 284.886
= 285 m/g = 436.78 % over Alcohol,