Sikander Aqeel

THE ALCOHOLIC LIVER DISEASE,

Aug 27th 2016, 11:10 am

Posted by aqeelsika

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(Two Polynucleotide in mathematical machine of Sikander Aqeel)

WILSON DISEASE

Lower-than-normal ALP levels

• 1 = Hypophosphatasia

• 2 = Malnutrition

• 3 = Wilson disease

•

• Wilson disease has a range of clinical manifestations, from an asymptomatic state to fulminate hepatic failure, chronic liver disease with or without cirrhosis, neurologic, and psychiatric manifestations

• Consider hepatic Wilson disease in the differential diagnosis of any unexplained chronic liver disease, especially in individuals younger than 40 years. The condition may also manifest as acute hepatitis. Hepatic dysfunction is the presenting feature in more than half of patients. The 3 major patterns of hepatic involvement are as follows:

• (1) chronic active hepatitis,

• (2) cirrhosis, and

• (3) fulminant hepatic failure. The most common initial presentation is cirrhosis.

2 = CIRRHOSIS

• Definitions of cirrhosis

• noun

• A chronic disease of the liver marked by degeneration of cells, inflammation, and fibrous thickening of tissue. It is typically a result of alcoholism or hepatitis.

• Chronic viral hepatitis is the main cause of chronic liver disease, cirrhosis and hepatocellular carcinoma throughout the world.

ABOUT CHOLESTASIS (8/28/2016)

Cholestasis means any condition in which bile flow is reduced or stopped. "Chole" refers to bile and "stasis" means "not moving." Bile flow may be blocked inside the liver, outside the liver, or in both places. Symptoms may include:

• Jaundice

• Dark urine

• Pale stool

• Easy bleeding

• Itching

• Ascites

• Chills

• Pain from the biliary tract or pancreas

• Enlarged gallbladder

Some causes of cholestasis include the following:

• Hepatitis

• Alcoholic liver disease

• Primary biliary cirrhosis

• Drug effects

• Hormonal changes during pregnancy

• A stone in the bile duct

• Bile duct narrowing

• Bile duct cancer

• Pancreatic cancer

• Inflammation of the pancreas

NATURAL ALCOHOL

TERTIARY NATURAL ALCOHOL

The Alcoholic liver disease with Urease and Arginase enzymes of liver, while Tertiary natural Alcohol being use for disease,

Tertiary Alcohol = C4-OH = 65.25 m/g

Tertiary Alcohol = 65.25 / 100 % = 0.6525

= 0.6525 * 55.494 % = 36.21

= 36.21 m/g = 55.494 percent Alcohol

Urease enzyme = Liver = 8.0 optimum pH = (substrate = Urea)

Arginase enzyme = Liver = 9.7 optimum pH = (substrate = Arginine amino acids)

Urease + Arginase enzyme = 17.7 optimum pH

55.494 % Alcohol = 36.21 m/g

= a2 + b2 = c2

= a2 (55.494 % Alcohol) + b2 (Urease + Arginase enzyme) = c2

= a2 36.21 + b2 17.7 = c2

= a2 1311.1641 + b2 313.29 = c2

= a + b = 1624.4541 = c2

= a + b = 1624.4541 / 40.30 = 40.30

= a + b = 40.30 / 2.5 (H2= A//T DNA) = 16.12

= a + b = 16.12 / 3.75 (H3= C///G DNA) = 4.29

= a + b = 4.29 * 50 ratio = 214.5

= a + b = 214.5 / 14.64A = 14.65A

= a + b = 15A = weak height of helix

= Alcohol = 15A / 10 mononucleotide = 1.5

= = 1.5A weak distance between two base pair,

Influenza A virus

When helix becomes small or short, then cell membrane becomes weak for invite to viruses,

For example

Urease enzyme = Liver = 8.0 optimum pH = (substrate = Urea)

Arginase enzyme = Liver = 9.7 optimum pH = (substrate = Arginine amino acids)

Urease + Arginase enzyme = 17.7 optimum pH

55.494 % Alcohol = 36.21 m/g

= a2 + b2 = c2

= a2 (55.494 % Alcohol) + b2(Urease + Arginase enzyme) = c2

= a2 36.21 + b2 17.7 = c2

= a2 1311.1641 + b2 313.29 = c2

= a + b = 1624.4541 = c2

= a + b = 1624.4541 + 62875.5459 = 64500 m/g hemoglobin

= a + b = 62875.5459 =?

Influenza A virus

= a + b = 62875.5459 / 9.7 pH of arginsea enzymes of liver = 6482.01

= a + b = 6482 / 7.0 pH of Urease enzymes of Urea = 926

= a + b = 926 / 8.0 pH of Lipase enzymes of pancreas = 115.75

= a + b = 115.75 = influenza A virus,

The influenza A virus particle or virion is 80–115.75-120 nm in diameter and usually roughly spherical, although filamentous forms can occur, Unusually for a virus, the influenza A genomeis not a single piece of nucleic acid; instead, it contains eight pieces of segmented negative-sense RNA (13.5 kilobases total), which encode 11 proteins (HA, NA, NP, M1, M2, NS1, NEP, PA, PB1, PB1-F2, PB2), The best-characterised of these viral proteins are hem agglutinin and neuraminidase, two large glycoproteins found on the outside of the viral particles. Neuraminidase is an enzyme involved in the release of progeny virus from infected cells, by cleaving sugars that bind the mature viral particles. By contrast, hem agglutinin is a lectinthat mediates binding of the virus to target cells and entry of the viral genome into the target cell, the hem-agglutinin (H) and neuraminidase (N) proteins are targets for antiviral drugs, These proteins are also recognized by antibodies, i.e. they are antigens, The responses of antibodies to these proteins are used to classify the different serotypes of influenza A viruses, hence the H and N in H5N1.

ALP - BLOOD TEST

Normal Results (ALP) tissues protein

The normal range is 44 to 147 IU/L (international units per liter)

The normal range = 147 IU/L for maximum weight and young age

The normal range = 44 IU/L for minimum weight and over age

INFLUENZA A VIRUSES

OVER ALCOHOL IN ALP BLOOD TEST (LOWER)

(ALP) tissues protein = 44 * 0.8229 (weak hydrogen) = 36.20

= 36.21 m/g = 55.494 % Alcohol,

INFLUENZA A VIRUSES

OVER ALCOHOL IN ALP BLOOD TEST (HIGHER)

(ALP) tissues protein = 147 * 0.2463 (die H) = 36.206