BRIGHT FUTURE OF MEMBRANE

(Bright Future of Membrane in cosmos of Sikander Aqeel)

The Membrane thickness which has important attention about gathering of chemical compounds, the heavy membrane gathers heavy value of lipids, proteins and carbohydrate, or lipids protein carbohydrate + membrane thickness = 212, or 112 is an basic structure of membrane and 100 % chemicals are equal to lipids protein carbohydrate of membrane, or 112 % thick membrane can catch to 100 % thick lipids protein carbohydrate, if membrane is 50 % thick, then 50 % thick membrane will catch to 56 % lipids protein carbohydrate,           

It is important to treatment of too over age, supposed you giving lipids protein carbohydrate through the medicines to patient for good health, but there are not effect on medicines, because there membrane is 25 % thick in too over age, they cannot catch to heavy lipids protein carbohydrate, so here in too over age need is health or treatment of thickness of membrane,  

IN HEALTH, 

Thickness of membrane = 112 % large type + Lipids protein carbohydrate 100 % large type = 212 % healthy membrane 

Or 112 % large type + 100 % large types = 212 % balance between chemicals and membrane thickness 

IN DISEASE  

Thickness of membrane = 25 % large type + Lipids protein carbohydrate 100 % large type = 125 % sick membrane 

Or 25 % large type + 100 % large types = 125 % unbalance between chemicals and membrane thickness 

So form of basic membrane and form of Lipids protein carbohydrate are two different forms,   

If first we will treat of thickness of membrane, then thick membrane will automatically catch to healthy Lipids protein carbohydrate in over age,    

Cell Membrane 

Cell Membrane = 40 % lipids + 40 % thick Membrane at fatty acid = 80 

Cell Membrane = 55 % protein + 55 % thick Membrane at amino acid side = 110 

Cell Membrane = 5 % carbohydrate + 17 % thick Membrane at carbon side = 22 

                                                                Total = 212 Membrane 

Cell Membrane compounds = 100 % 

Cell Membrane thickness = 112 % 

Total Membrane = 212

         = a2 + b2 = DNA helix

         = a2 46 Chromosomes  + b2 212 Membrane = c2  

         = a2 46 + b2 212 = c2 

         = a2 2116 + b2 44944 = c2 

         = a + b = 47060 = c2     

         = a + b = 47060 / 216.93 = 216.93

         = a + b = 216.93 / 2.5 (H2= A//T DNA) = 86.772

         = a + b = 86.772 / 3.75 (H3= C///G DNA) = 23.1392

         = a + b = 23.1392 * 50 ratio = 1156.96

         = a + b = 1157 / 34.01A = 34.01A

         = a + b = 34A = healthy height of helix  

        = DNA helix = 34A / 10 mononucleotide = 3.4

        =           = 3.4A healthy distance between two base pair, 

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DEPENDENCE OF MEMBRANE 

HYDROPHILIC HEAD AND HYDROPHOBIC TWO TAILS

1 = hydrophilic head = PO4 + CH2 + C2H2O2 = phosphate group + Glycerol,  

While Glycerol is a sweet syrupy trihdroxy alcohol obtained by saponification of fats and oils 

2 = hydrophobic two tail = saturated fatty acid + unsaturated fatty acid 

The membrane wall depend on micro-organisms of head and two tails, which of food chain occurs phospholipids + Glycerol + fatty acid, and this three compounds and water make healthy and strong to membrane wall, 

When membrane wall become sick or ill in over age, then they occurs not able to eat or absorb phospholipids + Glycerol + fatty acid in wall, and from this reasons the body bio functions becomes damage to make healthy body, if we repair to wall of membrane then may restart process of bio-health in body, 

Because healthy cell membrane wall = proteins transport = childhood 

And unhealthy cell membrane wall = zero transport of proteins = over age 

CELL MEMBRANE OF OVER AGE 

THIN MEMBRANE WITH SICK HEAD   

Cell Membrane = 10 % lipids + 10 % thick Membrane at fatty acid = 20 

Cell Membrane = 13.75 % protein + 13.75 % thick Membrane at amino acid side = 27.5 

Cell Membrane = 1 % carbohydrate + 8 % thick Membrane at carbon side = 9 

                                                                Total = 56.5 Membrane of over age 

Cell Membrane compounds = 24.75 % 

Cell Membrane thickness = 31.75 % 

Total Membrane = 56.5 

Total over age Membrane = 56.5 

Phosphate = 95 m/g

         = a2 + b2 = DNA helix

         = a2 Phosphate + b2 over Membrane = c2  

         = a2 95 + b2 56.5 = c2 

         = a2 9025 + b2 3192.25 = c2 

         = a + b = 12217.25 = c2     

         = a + b = 12217.25 / 110.53 = 110.53

         = a + b = 110.53 / 2.5 (H2= A//T DNA) = 44.212

         = a + b = 44.212 / 3.75 (H3= C///G DNA) = 11.78

         = a + b = 11.78 * 50 ratio = 589

         = a + b = 589 / 24.26A = 24.27A

         = a + b = 24A = less phosphate type height of helix  

        = DNA helix = 24A / 10 mononucleotide = 2.4

        =           = 2.4A less phosphate type distance between two base pair, 

Less phosphate type distance between two base pair = 2.4A – 0.1 % proteins = 2.3A unhealthy distance between two base pair, 

So phosphate 95 m/g = 0.1 % phosphate happening use only in membrane, and phosphate are not going into the cell for energy, because the DNA helix already weak or sick from over age, 

Basically in over age, the phosphate need occurs too much, because first membrane fills own self from phosphate and supply into the cell later, or in easy words, 

Less phosphate type distance between two base pair = 2.4A + 1 % phosphate = 3.4A healthy distance between two base pair, 

So the over age belongs with need of 1 % phosphate, while 0.1 % phosphate is equal to 95, PO4, m/g phosphate, so 1 % / 0.1 % = 10 times less phosphate in over age, 

therefore 95 * 10 = 950 m/g too much phosphate need in over age for healthy membrane, and this recovery of phosphate is too much hard but not impossible, 

(8/28/2016) 

Although the phosphate used in many portion of cell, but most important the phosphate and phosphate-lipids divides in cell’s water, nucleic membrane, cell membrane, and helix of DNA, if hydrophilic head is strong and filled with phosphate, naturally if hydrophilic head is not proper filled with phosphate, then hydrophilic head will not supply to phosphate into the cell’s water, nucleic membrane, cell membrane, and helix of DNA, 

THE PHOSPHATIDYLINOSITOL, 

The phosphate groups are also found on C-4 or C-5 of the inositol, the additional phosphate groups increase the charge of the hydrophilic head or polar head of this Phosphatidylinositol, 

So if charge increased of phosphate in hydrophilic head then membrane will be active to gather in polar head and transport protein into the cell, 

So we are using Palmitic acid in too weak membrane, for increase charge of polar head,  

CELL MEMBRANE OF OVER AGE 

THIN MEMBRANE WITH SICK HEAD   

Cell Membrane = 10 % lipids + 10 % thick Membrane at fatty acid = 20 

Cell Membrane = 13.75 % protein + 13.75 % thick Membrane at amino acid side = 27.5 

Cell Membrane = 1 % carbohydrate + 8 % thick Membrane at carbon side = 9 

                                                                Total = 56.5 Membrane of over age 

Cell Membrane compounds = 24.75 % 

Cell Membrane thickness = 31.75 % 

Total Membrane = 56.5 

Total over age Membrane = 56.5 

Palmitic acid = hexadecanoic acid = CH3 - (CH2)14 - COOH = 264 m/g

         = a2 + b2 = DNA helix

         = a2 Palmitic acid + b2 over age Membrane = c2  

         = a2 264 + b2 56.5 = c2 

         = a2 69696 + b2 3192.25 = c2 

         = a + b = 72888.25 = c2     

         = a + b = 72888.25 / 269.97 = 269.98

         = a + b = 269.98 / 2.5 (H2= A//T DNA) = 107.992

         = a + b = 107.992 / 3.75 (H3= C///G DNA) = 28.79

         = a + b = 28.79 * 50 ratio = 1439.5

         = a + b = 1440 / 37.94A = 37.95A

         = a + b = 38A = Palmitic acid type height of helix  

        = DNA helix = 38A / 10 mononucleotide = 3.8

        =           = 3.8A Palmitic acid type distance between two base pair, 

Palmitic acid type distance between two base pair = 3.8A – 0.4 % transport of proteins = 3.4A height of natural helix, from 30-carbon of Palmitic acid,  

The over age is empty from Palmitic acid for increase charge of hydrophilic head, because answer 0.4 % protein transporting into the cell, Palmitoylation is important for membrane localization of many proteins, 

If you are not fresh and strong in over age that yours membrane is empty from Palmitic acid for increase charge of hydrophilic head with the health, because answer 0.4 % protein transporting into the cell, or 0.1 % for outer head and 0.1 % for inner head and other 2 % for increase LDL levels in the blood,    

Excess carbohydrates in the body are converted to palmitic acid. Palmitic acid is the first fatty acid produced during fatty acid synthesis and the precursor to longer fatty acids. As a consequence, palmitic acid is a major body component of animals. In humans, one **ysis found it to comprise 21–30% (molar) of human depot fat, and it is a major, but highly variable, lipid component of human ** milk, Palmitate negatively feeds back on acetyl-CoA carboxylase (ACC), which is responsible for converting acetyl-CoA to malonyl-CoA, which in turn is used to add to the growing acyl chain, thus preventing further palmitate generation, In biology, some proteins are modified by the addition of a palmitoyl group in a process known as palmitoylation. Palmitoylation is important for membrane localization of many proteins. 

According to the World Health Organization, evidence is "convincing" that consumption of palmitic acid increases risk of developing ** diseases, based on studies indicating that it may increase LDL levels in the blood. Retinyl palmitate is an antioxidant and a source of vitamin A added to low fat milk to replace the vitamin content lost through the removal of milk fat. Palmitate is attached to the alcohol form of vitamin A, retinol, to make vitamin A stable in milk.

Rats fed a diet of 20% palmitic acid and 80% carbohydrate for extended periods showed alterations in central nervous system control of insulin secretion, and suppression of the body's natural appetite-suppressing signals from leptin and insulin (the key hormones involved in weight regulation),

Other research however, has indicated that the potential negative health effects of palmitic acid may be offset in combination with other fats,