(Bright Future of Membrane in cosmos of Sikander Aqeel)
The Membrane thickness which has important attention about gathering of chemical compounds, the heavy membrane gathers heavy value of lipids, proteins and carbohydrate, or lipids protein carbohydrate + membrane thickness = 212, or 112 is an basic structure of membrane and 100 % chemicals are equal to lipids protein carbohydrate of membrane, or 112 % thick membrane can catch to 100 % thick lipids protein carbohydrate, if membrane is 50 % thick, then 50 % thick membrane will catch to 56 % lipids protein carbohydrate,
It is important to treatment of too over age, supposed you giving lipids protein carbohydrate through the medicines to patient for good health, but there are not effect on medicines, because there membrane is 25 % thick in too over age, they cannot catch to heavy lipids protein carbohydrate, so here in too over age need is health or treatment of thickness of membrane,
IN HEALTH,
Thickness of membrane = 112 % large type + Lipids protein carbohydrate 100 % large type = 212 % healthy membrane
Or 112 % large type + 100 % large types = 212 % balance between chemicals and membrane thickness
IN DISEASE
Thickness of membrane = 25 % large type + Lipids protein carbohydrate 100 % large type = 125 % sick membrane
Or 25 % large type + 100 % large types = 125 % unbalance between chemicals and membrane thickness
So form of basic membrane and form of Lipids protein carbohydrate are two different forms,
If first we will treat of thickness of membrane, then thick membrane will automatically catch to healthy Lipids protein carbohydrate in over age,
Cell Membrane
Cell Membrane = 40 % lipids + 40 % thick Membrane at fatty acid = 80
Cell Membrane = 55 % protein + 55 % thick Membrane at amino acid side = 110
Cell Membrane = 5 % carbohydrate + 17 % thick Membrane at carbon side = 22
Total = 212 Membrane
Cell Membrane compounds = 100 %
Cell Membrane thickness = 112 %
Total Membrane = 212
= a2 + b2 = DNA helix
= a2 46 Chromosomes + b2 212 Membrane = c2
= a2 46 + b2 212 = c2
= a2 2116 + b2 44944 = c2
= a + b = 47060 = c2
= a + b = 47060 / 216.93 = 216.93
= a + b = 216.93 / 2.5 (H2= A//T DNA) = 86.772
= a + b = 86.772 / 3.75 (H3= C///G DNA) = 23.1392
= a + b = 23.1392 * 50 ratio = 1156.96
= a + b = 1157 / 34.01A = 34.01A
= a + b = 34A = healthy height of helix
= DNA helix = 34A / 10 mononucleotide = 3.4
= = 3.4A healthy distance between two base pair,
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DEPENDENCE OF MEMBRANE
HYDROPHILIC HEAD AND HYDROPHOBIC TWO TAILS
1 = hydrophilic head = PO4 + CH2 + C2H2O2 = phosphate group + Glycerol,
While Glycerol is a sweet syrupy trihdroxy alcohol obtained by saponification of fats and oils
2 = hydrophobic two tail = saturated fatty acid + unsaturated fatty acid
The membrane wall depend on micro-organisms of head and two tails, which of food chain occurs phospholipids + Glycerol + fatty acid, and this three compounds and water make healthy and strong to membrane wall,
When membrane wall become sick or ill in over age, then they occurs not able to eat or absorb phospholipids + Glycerol + fatty acid in wall, and from this reasons the body bio functions becomes damage to make healthy body, if we repair to wall of membrane then may restart process of bio-health in body,
Because healthy cell membrane wall = proteins transport = childhood
And unhealthy cell membrane wall = zero transport of proteins = over age
CELL MEMBRANE OF OVER AGE
THIN MEMBRANE WITH SICK HEAD
Cell Membrane = 10 % lipids + 10 % thick Membrane at fatty acid = 20
Cell Membrane = 13.75 % protein + 13.75 % thick Membrane at amino acid side = 27.5
Cell Membrane = 1 % carbohydrate + 8 % thick Membrane at carbon side = 9
Total = 56.5 Membrane of over age
Cell Membrane compounds = 24.75 %
Cell Membrane thickness = 31.75 %
Total Membrane = 56.5
Total over age Membrane = 56.5
Phosphate = 95 m/g
= a2 + b2 = DNA helix
= a2 Phosphate + b2 over Membrane = c2
= a2 95 + b2 56.5 = c2
= a2 9025 + b2 3192.25 = c2
= a + b = 12217.25 = c2
= a + b = 12217.25 / 110.53 = 110.53
= a + b = 110.53 / 2.5 (H2= A//T DNA) = 44.212
= a + b = 44.212 / 3.75 (H3= C///G DNA) = 11.78
= a + b = 11.78 * 50 ratio = 589
= a + b = 589 / 24.26A = 24.27A
= a + b = 24A = less phosphate type height of helix
= DNA helix = 24A / 10 mononucleotide = 2.4
= = 2.4A less phosphate type distance between two base pair,
Less phosphate type distance between two base pair = 2.4A – 0.1 % proteins = 2.3A unhealthy distance between two base pair,
So phosphate 95 m/g = 0.1 % phosphate happening use only in membrane, and phosphate are not going into the cell for energy, because the DNA helix already weak or sick from over age,
Basically in over age, the phosphate need occurs too much, because first membrane fills own self from phosphate and supply into the cell later, or in easy words,
Less phosphate type distance between two base pair = 2.4A + 1 % phosphate = 3.4A healthy distance between two base pair,
So the over age belongs with need of 1 % phosphate, while 0.1 % phosphate is equal to 95, PO4, m/g phosphate, so 1 % / 0.1 % = 10 times less phosphate in over age,
therefore 95 * 10 = 950 m/g too much phosphate need in over age for healthy membrane, and this recovery of phosphate is too much hard but not impossible,
(9/2/2016)
Although the phosphate used in many portion of cell, but most important the phosphate and phosphate-lipids divides in cell’s water, nucleic membrane, cell membrane, and helix of DNA, if hydrophilic head is strong and filled with phosphate, naturally if hydrophilic head is not proper filled with phosphate, then hydrophilic head will not supply to phosphate into the cell’s water, nucleic membrane, cell membrane, and helix of DNA,
THE PHOSPHATIDYLINOSITOL,
The phosphate groups are also found on C-4 or C-5 of the inositol, the additional phosphate groups increase the charge of the hydrophilic head or polar head of this Phosphatidylinositol,
So if charge increased of phosphate in hydrophilic head then membrane will be active to gather in polar head and transport protein into the cell,
So we are using Oleic acid in too weak membrane, for increase charge of polar head,
CELL MEMBRANE OF OVER AGE
THIN MEMBRANE WITH SICK HEAD
Cell Membrane = 10 % lipids + 10 % thick Membrane at fatty acid = 20
Cell Membrane = 13.75 % protein + 13.75 % thick Membrane at amino acid side = 27.5
Cell Membrane = 1 % carbohydrate + 8 % thick Membrane at carbon side = 9
Total = 56.5 Membrane of over age
Cell Membrane compounds = 24.75 %
Cell Membrane thickness = 31.75 %
Total Membrane = 56.5
OLEIC ACID
Total over age Membrane = 56.5
Oleic acid = fatty acid that occurs naturally
Oleic acid = C18H34O2 = 290.5 m/g
= a2 + b2 = DNA helix
= a2 Oleic acid + b2 over age Membrane = c2
= a2 290.5 + b2 56.5 = c2
= a2 84390.25 + b2 3192.25 = c2
= a + b = 87582.5 = c2
= a + b = 87582.5 / 295.94 = 295.94
= a + b = 295.94 / 2.5 (H2= A//T DNA) = 118.376
= a + b = 118.376 / 3.75 (H3= C///G DNA) = 31.56
= a + b = 31.56 * 50 ratio = 1578
= a + b = 1578 / 39.72A = 39.72A
= a + b = 40A = Oleic acid type height of helix
= DNA helix = 40A / 10 mononucleotide = 4.0
= = 4.0A Oleic acid type distance between two base pair,
Oleic acid type distance between two base pair = 4.0A – 0.6 % transport of proteins = 3.4A height of natural helix, from 18-carbon of Oleic acid,
The over age is empty from Oleic acid for increase charge of hydrophilic head, because answer 0.6 % protein transporting into the cell, Palmitoylation is important for membrane localization of many proteins,
If you are not fresh and strong in over age that yours membrane is empty from Oleic acid for increase charge of hydrophilic head with the health, because answer 0.6 % protein transporting into the cell, or 0.1 % for outer head and 0.1 % for inner head and other 0.4 % for responsible of the hypertensive (blood pressure reducing),
Oleic acid is the most abundant fatty acid in human adipose tissue, and second in abundance in human tissues overall only to palmitic acid,
The biosynthesis of oleic acid involves the action of the enzyme stearoyl-CoA 9-desaturase acting on stearoyl-CoA. In effect, stearic acidic dehydrogenated to give the monounsaturated derivative oleic acid.
Oleic acid (in triglyceride form) is included in the normal human diet as a part of animal fats and vegetable oils.
Oleic acid often a matter of life and death,
Oleic acid is a common monounsaturated fat in human diet. Monounsaturated fat consumption has been associated with decreased low-density lipoprotein (LDL) cholesterol, and possibly increased high-density lipoprotein (HDL) cholesterol However; its ability to raise HDL is still debated.
Oleic acid may be responsible for the hypertensive (blood pressure reducing) effects of olive oil, Adverse effects also have been do**ented,